Stuffed on 4th & 1 in OT; McVay criticized for play design and personnel choice.

In Week 5 2025 overtime against the San Francisco 49ers, McVay elected to go for a game-winning touchdown on 4th & 1 at the 11-yard line rather than kick a tying field goal. The decision to go for it was debatable, but the actual play call drew widespread criticism; instead of using motion, misdirection, or creative concepts, the Rams ran a straightforward inside run into a stacked defensive front, putting the ball in Williams's hands rather than Matthew Stafford. The play was stuffed, the Rams lost 26-23, and dropped to 3-2, contributing to the Rams' failure to win the NFC West over the Seahawks.