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ArticleWeek 4 Rushing Matchups
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Denver's run defense has been the NFL's most disappointing unit this season. Last year, it allowed the fewest fantasy points in the NFL to opposing running backs. In 2026, that has changed. So far, they've been the worst in the league through three weeks by EPA per rush play, allowing 143.7 rushing yards per game, the third-most in the NFL, and 389 total rushing yards to opposing backs, the second-most in football.

STACKED’s take

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Denver's run defense collapsed from best to worst; ideal matchup for McCaffrey's efficiency.

McCaffrey faces Denver's run defense, which has been the NFL's most disappointing unit this season after allowing the fewest fantasy points to opposing running backs last year. In 2026, Denver is the worst in the league by EPA per rush play, allowing 143.7 rushing yards per game (third-most in NFL) and 389 total rushing yards to opposing backs (second-most in football). McCaffrey remains one of the most efficient backs in football with a positive run rate north of 90%, and now he's finally getting the volume to match that efficiency, setting up about as clean a matchup as he could ask for.

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